Diterpene alkaloids
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Diterpene alkaloids are natural products of the terpene alkaloid type.[1]
Occurrence
[edit]Veatchine is found in the bark of Garrya veatchii, a member of the Cup Catkins family.[2] Aconitine is the main alkaloid in aconite.[3]
Structure
[edit]Diterpene alkaloids can be divided into two groups: The diterpene alkaloids, characterized by a C20 parent body, and the norditerpene alkaloids, which are based on a hexacyclic C19 parent body.[1]
Representatives
[edit]Diterpene group
[edit]Among the C20 alkaloids is the atisine-type (atisine, hetidine, hetisine) and the veatchine-type (Veatchin, Napellin).[1]
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Atisine -
Veatchin
Northern iterpene group
[edit]The C19 alkaloids include, among others, the aconitine type (aconitine, delphinine) and the lycoctonine type (Lycoctonin, Browniin).[1]
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(+)-Lycoctonine
-Lycoctonine_Structural_Formula_V2.svg)
Properties
[edit]Aconitine has cardiac arrhythmic and antipyretic properties and is one of the most toxic plant compounds.[2]
References
[edit]- ^ a b c d Entry on Diterpen-Alkaloide. at: Römpp Online. Georg Thieme Verlag, retrieved {{{Datum}}}.
- ^ a b Eberhard Breitmaier (1997), Alkaloide, Wiesbaden: Springer Fachmedien, pp. 83f., ISBN 9783519035428
- ^ Rudolf Hänsel, Otto Sticher (2007), Pharmakognosie Phytopharmazie (8 ed.), Heidelberg: Springer Medizin Verlag, p. 1466, ISBN 9783540265085